Illustration by Mark Allen Miller
Imagine an old laboratory mouse – the bad hair, the wrong turns in the maze, the laziness around, just imagine that the mouse was operatively linked to another, more youthful mouse … un Then within a few weeks she will get younger. When the scientists did, "they found that the old mouse showed less age-related diseases, such as diabetes, heart disease, and Alzheimer's," says Jesse Karmazin, M. D.
. For Dr. Karmazin you are the old mouse. The 33-year-old Stanford-trained doctor is not about to sew you to a college freshman. However, based on recent research, he assumes that people have the same age-related benefit from a dose of young blood
Dr. Karmazin founded Ambrosia in 2016, a company that will infuse you with one to two liters of a 16- to 25-year-old plasma. For up to $ 12,000. So far, he says, many of his 150 patients report that they feel better and achieve better results with just one treatment each year. He admits that it sounds totally scary, even if transfusions are of course not a new science. "We use it only for a different purpose."
Experiments on the "parabiosis" of the mouse, the anatomical connection of two individuals, dates back to 1864; The findings in young and old mice were reported in the 1950s. But until 2002, when the scientists at Stanford were at a routine meeting, there was an investigation into getting old and why components of your body should age rather than separate. Someone has hypothesized: Your circulation is reaching everything in your body, so your blood may contain chemicals that will make you age.
Soon they put together mice to find out. Their study, published in Nature, showed that the old mice showed increased production of progenitor cells (organ repairers that diminish with age) and better brain, muscle, and liver function. They even looked younger. The theory: Young blood dilutes anti-inflammatory agents in old blood, so that possibly no progenitor cells are formed.
The National Institutes of Health believe that the method is promising in deciphering human aging. In 2017, more than four times as many parabiosis studies were funded as in the previous year. However, positive results were only achieved in mice – and some scientists believe that Dr. Karmazin releases blood prematurely because what's in your veins may only be part of it's history.
"Connected mice do not just share blood," says Dr. Michael Conboy, who helped shape the Nature study. "They share organ systems. The younger mouse can absorb and transport more nutrients from food. and in our study, the young man even led the old man around and trained him more. "Maybe the magic is in the blood, maybe not.
Or maybe there is no magic at all. The annals of medicine are full of overheated treatments that work in mice but not in men. In the very first plasma transfusion study on humans, which was conducted in Stanford and funded by another young company, Alkahest, no humans were killed (transfusions have a rare risk of fatal complications), but no brain anti-aging effects.
Therefore, Dr. Karmazin a follow-up study. The data – from 81 patients who funded their own treatments – show an improvement in markers of Alzheimer's disease, inflammation and heart disease, claims Dr. Ruth. Karmazin. However, it will be published in 2019 at the earliest. Ambrosia is on the rise and has just updated its website, so you can schedule treatments in six cities (Phoenix, LA, San Francisco, Tampa, Omaha and Houston) and pay via PayPal.
But why should not you save your 12 major and wait for more studies to be published? In the meantime, focus on a handful of cheaper strategies to delay the longevity cycle:
Queue Up the Takeout
New nutritional research has shown that the Indian spice turmeric is one of the most effective anti-inflammatory drugs in the world. Order curry or use the spice in everything: eggs, vegetables, rice.
Keep Up Cardio
In one study, men who performed four sets of four-minute high-intensity intervals (three times a week) improved markers of inflammation more than men who performed 40- to 65-minute strength training.
Mix Mind and Body
Under stress, you produce an inflammatory protein. However, mind-body practices such as meditation, tai chi and yoga could prevent this, according to a study in Frontiers of Immunology.